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A Moment in History

Self-portrait, Henry Vandyke Carter, MD (Public Domain)
Self-portrait, Henry Vandyke Carter, MD (Public Domain)

Henry Vandyke Carter, MD
(1831 – 1897)

English physician, surgeon, medical artist, and a pioneer in leprosy and mycetoma studies.  HV Carter was born in Yorkshire in 1831. He was the son of Henry Barlow Carter, a well-known artist and it is possible that he honed his natural talents with his father. His mother picked his middle name after a famous painter, Anthony Van Dyck. This is probably why his name is sometimes shown as Henry Van Dyke Carter, although the most common presentation of his middle name is Vandyke.

Having problems to finance his medical studies, HV Carter trained as an apothecary and later as an anatomical demonstrator at St. George’s Hospital in London, where he met Henry Gray (1872-1861), who was at the time the anatomical lecturer. Having seen the quality of HV Carter’s drawings, Henry Gray teamed with him to produce one of the most popular and longer-lived anatomy books in history: “Gray’s Anatomy”, which was first published in late 1857.  The book itself, about which many papers have been written, was immediately accepted and praised because of the clarity of the text as well as the incredible drawings of Henry Vandyke Carter.

While working on the book’s drawings, HV Carter continued his studies and received his MD in 1856.

In spite of initially being offered a co-authorship of the book, Dr. Carter was relegated to the position of illustrator by Henry Gray and never saw the royalties that the book could have generated for him. For all his work and dedication, Dr. Carter only received a one-time payment of 150 pounds. Dr.  Carter never worked again with Gray, who died of smallpox only a few years later.

Frustrated, Dr. Carter took the exams for the India Medical Service.  In 1858 he joined as an Assistant Surgeon and later became a professor of anatomy and physiology. Even later he served as a Civil Surgeon. During his tenure with the India Medical Service he attained the ranks of Surgeon, Surgeon-Major, Surgeon-Lieutenant-Colonel, and Brigade-Surgeon.

Dr. Carter dedicated the rest of his life to the study of leprosy, and other ailments typical of India at that time. He held several important offices, including that of Dean of the Medical School of the University of Bombay. In 1890, after his retirement, he was appointed Honorary Physician to the Queen.

Dr. Henry Vandyke Carter died of tuberculosis in 1897.

Personal note: Had history been different, this famous book would have been called “Gray and Carter’s Anatomy” and Dr. Carter never gone to India. His legacy is still seen in the images of the thousands of copies of “Gray’s Anatomy” throughout the world and the many reproductions of his work available on the Internet. We are proud to use some of his images in this blog. The image accompanying this article is a self-portrait of Dr. Carter. Click on the image for a larger depiction. Dr. Miranda

Sources:
1. “Obituary: Henry Vandyke Carter” Br Med J (1897);1:1256-7
2. “The Anatomist: A True Story of ‘Gray’s Anatomy” Hayes W. (2007) USA: Ballantine
3. “A Glimpse of Our Past: Henry Gray’s Anatomy” Pearce, JMS. J Clin Anat (2009) 22:291–295
4. “Henry Gray and Henry Vandyke Carter: Creators of a famous textbook” Roberts S. J Med Biogr (2000) 8:206–212.
5. “Henry Vandyke Carter and his meritorious works in India” Tappa, DM et al. Indian J Dermatol Venereol Leprol (2011) 77:101-3


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Azygos venous system

The azygos venous system drains the posterior aspect of the thorax via the posterior intercostal veins It also connects the vascular territories of the superior vena cava and the  inferior vena cava, and is the superior continuation of the lumbar veins. The azygos system was first described by Bartolomeo Eustachius (c1500 - 1574).

The name azygos comes from the Greek [ζεύγος] and means “unyoked” or better “asymmetrical”. This system is different on each side of the body, also having important anatomical variations.

The azygos vein (Lat: vena azygos major) is the larger vein of the azygos system and is found on the right side of the body. It begins at the level of the first or second lumbar vertebra as a continuation of the right ascending lumbar vein; sometimes by a branch from the right renal vein or from the inferior vena cava. It enters the thoracic cavity through the aortic hiatus of the respiratory diaphragm, and ascends along the right side of the vertebral column to level of the fourth thoracic vertebra, where it arches forward over the root of the right lung, at this point the vein is called the azygos arch, which terminates in the posterior aspect of the superior vena cava (SVC) just superior to the point where the SVC enters the pericardium.

In the thorax, the azygos vein is found to the right of the thoracic duct on the right side of the descending aorta; it lies upon the intercostal arteries and is partly covered by the parietal pleura.

The azygos vein receives the right subcostal vein, nine or ten right posterior intercostal veins, the hemiazygos vein, the accessory hemiazygos vein, the right superior intercostal vein, and several minor esophageal, mediastinal, and pericardial veins.

The left side of this system is more complex and presents with more anatomical variations. Its main component is the hemiazygos vein (Lat: vena azygos minor), also known as the left lower azygos vein. It is a continuation of the left ascending lumbar vein, and it sometimes may arise from the left renal vein and passes into the thorax usually through the left aortic crus of the respiratory diaphragm. It ascends to the level of the 7th or 8th thoracic vertebra where it crosses the midline posterior to the esophagus, descending aorta and thoracic duct to empty into the right-sided azygos vein.  It receives the left subcostal vein and three to four lower posterior intercostal veins, and some esophageal and mediastinal veins.

1. Right brachiocephalic vein 2. Right supreme intercostal vein 3. Superior vena cava 4. Right superior intercostal vein 5. Hemiazygos vein 6. Right subcostal vein 7. Right ascending lumbar vein 8. Left brachiocephalic vein 9. Left internal jugular vein 10. Left supreme intercostal vein 11. Left superior intercostal vein 12. Left posterior intercostal veins 13. Accessory hemiazygos vein 14. Left subcostal vein 15. Left ascending lumbar vein 16. Inferior vena cava
  1. Right brachiocephalic vein
  2. Right supreme intercostal vein
  3. Superior vena cava
  4. Right superior intercostal vein
  5. Hemiazygos vein
  6. Right subcostal vein
  7. Right ascending lumbar vein
  8. Left brachiocephalic vein
  9. Left internal jugular vein
  10. Left supreme intercostal vein
  11. Left superior intercostal vein
  12. Left posterior intercostal veins
  13. Accessory hemiazygos vein
  14. Left subcostal vein
  15. Left ascending lumbar vein
  16. Inferior vena cava
The second component of the left azygos system is the accessory hemiazygos vein, also known as the left upper hemiazygos. This component varies in size depending on the third venous drainage component of the left posterior thoracic wall. This is the left superior intercostal vein (see attached diagram).

The accessory hemiazygos, similar to the hemiazygos vein will cross the midline posterior to the esophagus, descending aorta and thoracic duct to empty into the right-sided azygos vein. It may do so by a common vein or by a separate vein as shown in the attached diagram. If there is a common vein the hemiazygos is considered to be the inferior component and the hemiazygos is considered to be the superior component.

The left superior intercostal vein receives three or four posterior intercostal veins, and empties into the left brachiocephalic vein. In rare cases of absence of the hemiazygos vein, this left superior intercostal vein will extend as low as the fifth or sixth intercostal space.

Although not considered to be part of the azygos system, the drainage of the posterior thoracic wall is completed by the right and left supreme intercostal veins which empty the posterior aspect of the first intercostal space into the left and right brachiocephalic veins respectively.

The azygos system of veins constitute an important collateral venous circulation pathway which can be seen in action in cases of blockage of the superior or inferior vena cavae.
 
Sources:
1. “Gray’s Anatomy” Henry Gray, 1918
2. "Tratado de Anatomia Humana" Testut et Latarjet 8th Ed. 1931 Salvat Editores, Spain
3. "Gray's Anatomy" 38th British Ed. Churchill Livingstone 1995

4. "Reconstructive Anatomy: A Method for the Study of Human Structure: Arnold, M WB Saunders1968
Image modified from the original from Arnold (4)